SYNTHESIS AND EVALUATION OF THE BIOLOGICAL PROPERTIES OF BORON-CONTAINING AND BORON-OMITTED CAPSAICIN DERIVATIVES ON HUMAN CANCER CELL LINES

Synthesis and evaluation of the biological properties of boron-containing and boron-omitted capsaicin derivatives on human cancer cell lines

Boron-containing and boron-omited derivatives based on the structural motif of capsaicin have been synthesized.The vanillyl amide moiety neck gaiter of the parent capsaicin molecule was retained and the boron atom was incorporated into the aliphatic region.All new compounds have been fully characterized using various analytical techniques including

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Low-Load Limit in a Diesel-Ignited Gas Engine

The lean-burn capability of the Diesel-ignited gas engine combined with its potential for high efficiency and low CO 2 emissions makes this engine concept one of the most promising Ammunition alternative fuel converters for passenger cars.Instead of using a spark plug, the ignition relies on the compression-ignited Diesel fuel providing ignition ce

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Group Cognitive-Behavior Therapy or Group Metacognitive Therapy for Obsessive-Compulsive Disorder? Benchmarking and Comparative Effectiveness in a Routine Clinical Service

Cognitive-behavior therapy (CBT), delivered in an individual or group format, is the recommended treatment of choice for Obsessive-Compulsive Disorder (OCD), but no studies have benchmarked the outcomes for group CBT in real-world clinical settings.The first aim of this evaluation was to benchmark the outcomes for group CBT in a sample of 125 patie

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